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Principles of prescribing during Pregnancy
- Where possible use nondrug therapy
- Prescribe drugs only when definitely needed.
- Choose the drug having the best safety records over time
- Avoid newer drugs, unless safety is clear established
- Over the Counter [OTC] cannot be assumed to be safe
- As far as possible, avoid medication is the initial 10 weeks of gestation
- Use the lowest effective dose
- Use drugs for the shortest period necessary
- If possible, give drugs intermittently
There are many concerns of permanent harm to the baby whenever any drug is administered to pregnant woman. Maternal medication can also increase the incidence of abortion, foetal death, and premature/delayed labor or create perinatal problems. Moreover, these are pronounced and progressive physiological changes during pregnancies which can affect drug disposition. As such, prescribing for the pregnant woman requires a lot of skills. Information is mostly derived from anecdotal reports & retrospective studies.